Near the end of Act 5.3 in Macbeth, we have him saying:
That should applaud again. Pull’t off, I say,
What Rhubarb, Cyme, or what Purgative drug
Would scour these English hence: hear’st thou of them?
We know that Bacon was fanatic about studying herbs as drugs. Was William of Stratford also?
Bacon wrote when listing purgative herbs:
“Astringents purgative, which, having by their purgative or expulsive power thrust out the humours, leave behind them astrictive virtue:
RHUBARB, especially that which is toasted against the fire: myrobalanes, tartar, tamarinds, an Indian fruit like green damascenes.”